1. Ground and surface water quality evaluation of Thrissur(2010) Nisha.A.R*., Vineetha.C.B**., Dhanya.V.R*** and Sreelekha.K.P**** Asian Journal of Chemical and environmental research 3(3),92-94
Dept. of Pharmacology and Toxicology,COVAS,Manuthy.
The present investigation was carried out to determine the physio-chemical parameters of drinking water samples collected from different places of Thrissur district of Kerala state. The parameters such as pH, temperature, total dissolved solids, turbidity, alkalinity, hardness, chlorides, sulfates and iron have been analysed. The physio-chemical properties revealed that the drinking water quality in Thrissur area is generally within the maximum permissible limit (MPL) set by WHO and hence safe for domestic and irrigation purpose.
*drnishaar@gmail.com,**
Effect of alcoholic extracts of the seeds of Nelumbo nucifera on spontaneous motor activity in rats.(2010) P.K.Deepa., P.T.A.Usha*., A.M.C.Nair and K.T.Prasannakumari Indian Veerinary Journal. 87(1): 17-18
Dept. of Pharmacology and Toxicology,COVAS,Manuthy
Spontaneous motor activity was studied after administration of extract of seeds of Nelumdo nucifera (red and white type) @400mg/kg and 600 mg/kg orally in rats.All the treated groups showed reduction in spontaneous motor activity. Nelumbo nucifera red type @600mg/kg produced most potent effects among the extract treated groups.Chlorpromazine produced more effect when compared with extract treated groups.
*ushapta2003@yahoo.co.in
Hypoglycaemic effect of a combination of Pleurotus ostreatus, Murraya koenigii and Aegle marmelos in diabetic rats Saritha Krishna and P.T.A.Usha(2009) Indian J of Anim Sci 79(10): 986-987
Dept. of Pharmacology and Toxicology,COVAS,Manuthy
This study was conducted to assess the hypoglycaemic effect of a combination of Pleurotus ostreatus, Murraya koenigii and Aegle marmelos in alloxan induced diabetic rats. A combination of P.ostreatus(250mg/kg), M. koenigii (250mg/kg)and A.marmelos (250mg/kg) was administered orally to diabetic rats and the effects were compared with individual plant extracts. The study revealed that the combination produced synergistic effects on lowering of blood glucose levels, serum cholesterol and triglyceride levels when compared to individual plant extracts. The effect of the combination was comparable to the reference drug glibenclamide.
Analysis of cadmium levels in field samples of cattle in Eloor industrial area and its impact on cattle disease patterns. Nisha,A.R., Chandrasekharan Nair,A.M.,Gopakumar,N* and Joy.A.D** (2009)Pollution research.Issue.28(2):199-202 Dept. of Pharmacology and Toxicology,COVAS,Manuthy
A study was undertaken in Eloor industrial area of Kerala to find out the extent of environmental pollution with cadmium and its impact on cattle health. Area around Fertilizers and Chemicals Travancore (Eloor south), Indian Aluminium Company(Alupuram), Binani Zinc (Binanipuram) and Hindustan Insecticides Limited (Eloor North) were selected for study. As the first step survey and retrospective analysis of cases were done in Eloor and nearby Muppathadam veterinary hospitals.The survey revealed that almost all farmers are facing various problems in maintaining livestock. Ahigh incidence of digestive diorders, deficiency diseases and repeat breeders are suggestive of cadmium toxicity. The field samples like water, sludge and forages were collected from the industrial field localities. The cadmium content in the field samples were estimated by atomic absorption spectrophotometer. University livestock farm, Mannuthy is taken as the control area. The cadmium content in the field samples were significantly higher than the control. The water quality was assessed by testing alkaline hardness,noncarbonate hardness,total alkalinity,hydroxide alkalinity,carbonate alkalinity, bicarbonate alkalinity,total acidity,mineral acidity and chloride.The values obtained for calcium hardness,carbonate hardness,chloride and total alkalinity were significantly higher than samples from Mannuthy.It was concluded that water and forage samples of Eloor Industrial area were contaminated with cadmium causing health hazards to cattle. *ngk38@yahoo.com,**adjoyp@yahoo.com
Assessment of DDT residues in cattle of Eloor Industrial area.
A.K.Deepa*,P.T.A.Usha and N.Gopakumar (2008) Pollution Research 27(2):315-316
Dept. of Pharmacology and Toxicology,COVAS,Manuthy
A study was conducted in Eloor Industrial area of Ernakulam district of Kerala to assess the level of environmental pollution by pesticide manufacturing factories in this region.Samples like blood,urine dung,and milk were collected from cattle belonging to this area and were analysed for DDT residues using Gas Liquid Chromatography.Biochemical and haematological parameters were also analysed. All the samples were compared with samples collected from University livestock farm,Mannuthy where there was no chance of industrial pollution.Samples from Eloor Industrial area contain DDT levels (ppm) of 0.6322 + 0.3741(serum) ,0.0342 + 0.0002 (urine), 0.1365 + 0.0055 (milk) and 0.3015 + 0.0476 (dung).Corresponding DDT values from University livestock farm,Mannuthy were 0.2518 + 0.0650 (serum),0.0133 + 0.0005 (urine),0.0257 + 0.0034 (dung) and DDT could not be detected in any samples of milk from University livestock farm,Mannuthy.Haematological values,total protein and albumin remained within the normal range but serum enzymes ALT and AST showed significant difference between Mannuthy and Eloor Industrial area.
*deepa_ak1@rediffmail.com